Pabrinex IM

Michael Proctor 22/08/15 General Questions & Answers


Could anyone advise a standard dose and frequency for Pabrinex IM as prophylaxis, to be integrated into a prescribed community alcohol detox please.

Thank you in advance :-)


Post a reply

Natasha Diaz 23/08/15

Hi Michael

I have always used IM Pabrinex according to the Archimedes guidelines of 1 pair BD for 7 days. 1 pair consists of vial 1 = 5mls and vial 2 = 2mls so 7mls total dose).

Several years ago I went to a Pabrinex study day and met several community alcohol workers who reported successfully using IM Pabrinex in the community, especially with the homeless and difficult to engage. I work in an acute hospital setting so mainly use IV Pabrinex. Would you be able to share your community detox policy as I am looking into formulating a pathway from acute care into the community and I would like to see how other services work.

Whereabouts do you work?

Kind regards

Natasha Diaz
Senior Substance Misuse Nurse
Substance2Solution- Northamptonshire CRI
[log in to view email address]

Adrian Brown 26/08/15

I have attached the most recent Archimedes clinical leaflet, which is aimed at IV on wards, but they have a handy card sized info sheet which says the same as Natasha stated. I'll see if I have a scan of that.

Our practice when we gave parenterovite, back in the 90s was one of each once a day, on arrival for daily dispensing of detox meds (ie chlordiazepoxide).

Associated files and links:

Michael Proctor 29/09/15

Thanks for the reply Natasha :) I would really like to share that information with you but unfortunately we appear to be in the same boat as you.Taking early discharges from a hospital setting into the community is something I will attempt to address in the near future I hope.

Kind Regards,


Michael Proctor 29/09/15

Thanks for your help Adrian :) I have so far managed to formulate a PGD that my employer has accepted, but was rejected by Sefton CCG. Their rationale for refusing to facilitate pabrinex in a community setting was due to lack of evidence of it efficacy in a community setting, and it being more appropriate in an inpatient setting which as you will probably know as an alcohol nurse is absolute blasphemy. It would be handy if I could make contact and network with other service providers nationwide who have successfully managed to facilitate this medication in a community setting.

Kind Regards,


Adrian Brown 29/09/15

I wonder if they'd apply the same logic to other drugs given at home via clinics rather than in hospital?

Dr Irena Guerrini has researched community /outpatient settings I believe.

Also plenty of detail

Adrian Brown 29/09/15

Dr Irena Guerrini was certainly researching the community setting and might have recent data.
I wonder what is their evidence that Pabrinex is less efficacious in the community than in the hospital and if they'd apply that logic to other drugs for other conditions?

View our private forums